metaphactory is used by this German pharmaceutical company to power a Knowledge Graph-based R&D Explorer providing actionable insights for target and drug discovery and drug safety reporting. The R&D Exoplorer offers a unified information hub for proprietary and publicly available research data related to performed clinical studies, reported adverse events, drug and substance data, molecular data, and information on indications. It supports researchers in their drug discovery processes by allowing them to connect the dots between these disparate pieces of information, perform similarity matches between indications, studies and subjects, and exploratively investigate interesting targets.  

Preclinical studies are a requirement for obtaining approval for clinical studies from regulatory agencies. They help assess drug candidates and determine safe doses for studies in humans. This Swiss healthcare company used metaphactory to build a FAIR in-vivo data sharing platform that allows researchers, bio-informaticians and lab scientists to browse, search, access, and extract meaningful insights obtained during preclinical studies and leverage this information when preparing electronic regulatory submissions required by regulatory agencies for entering clinical trials. The data sharing platform does not only deliver insights into dosages used in pre-clinical studies and potential side effects, but it also provides a valuable basis for understanding how certain compounds could be reused, repurposed, or repositioned.